At present, the product has entered Phase III clinical trial stage, China is also under study. 目前国际上已有产品进入三期临床试验阶段,中国也正在研究中。
Up to now, MISO ( misonidazole) is the only agent that has entered the phase III clinical trial. However, serious neurotoxicity limits its further clinical application. 迄今国际上唯一进入临床Ⅲ期试验的放射增敏剂是MISO(Uisonidazole),但由于其神经毒性严重未能在临床实践上推广。
At present, rimonabant ( SR141716) has already been applied to phase III clinical trial and it can effectively reduce body weight without causing serious adverse effects. 目前利莫那班(rimonabant,SR141716)已经进入III期临床试验,能有效地降低体重,且无明显不良反应。